Sikeston is located in Missouri. About 16,330 people live here. Between 2010 and 2020, the population declined from 16,318 to 16,291. The region is at 100 meters above sea level. The area covers about 45.7 square kilometers. There are about 550 streets in Sikeston. The region was founded in 1860. The postal codes are 63801. The dialing code is 573. Sikeston is city in Scott and New Madrid counties in Missouri, United States. Among other things, Sikeston has hotels, restaurants, supermarkets, schools, banks and pharmacies. More information at
www.sikeston.org.