US Highway 281 in Mellette Township, South Dakota

US Highway 281 in Spink County is a two-lane expressway. It runs in a north-south direction and crosses 149th Street, 150th Street, 151st Street, 152nd Street, 153rd Street, SD Highway 20, Center Road, 172nd Street, 171st Street, 170th Street, 169th Street and 168th Street. It ends in a cul-de-sac and connects Mellette Township, Redfield Township, Three Rivers Township and Jefferson Township. This street is part of the highway "281". US Highway 281 also exists in Tulare Township and Garfield Township.