Photo of Spring Branch west of Rittiman Road in Spring Branch, Texas, taken in June 2007. – Cohee at English Wikipedia, Public domain – Wikimedia Commons Spring Branch is located in Comal County. The region is located on the body of water Guadalupe River. About 206 people live here (as of 2020). The area covers about 4.9 square kilometers. There are about 32 streets in Spring Branch. The region was founded in 1852. The postal codes are 78070. Spring Branch is city in Comal County, Texas, United States.